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Ambien is a drug that needs prescription that is used for short-term treatment of insomnia including some brain disorders. It is a short-acting nonbenzodiazepine that inhibitory neurotransmitter. It works very fast and has a short half-life of 2-3 hours. It has hypnotic effect like those drugs that belongs to benzodiazepines but it has distinct property that is classified as imidazopyridine.
It has also an anticonvulsant and muscle relaxant properties. Its benefits start to effect at 10 and 20 times the dose of required sedation and for this reason it has never been approved for either seizure prevention and muscle relaxant. For increased doses it induces negative side effect that includes amnesia and hallucinations. The patent is owned by Sanofi-Aventis and the US FDA approved 13 generic versions of this drug. This drug is available in 5 mg and 10 mg for oral administration. The 5 mg tablet is in capsule shape, pink in color, film coated with AMB 5 debossed in one of its side and 5401 on the other side. The 10 mg tablet is also in capsule shape, white in color, also film coated, with AMB 10 debossed in one of its side and 5421 on the other side. The dose of Ambien should be individualized on the conditions of the patient. The recommended dose is 10 mg OD before bedtime and it should not exceed more than 10 mg per day. For elderly patients and also patients with hepatic disorders the recommended dose is 5 mg once before bedtime. The effect of the drug is slowed by ingestion or immediately after a certain meal.
It is also recommended that general support measures should be used along with this treatment. Intravenous fluid should be administred as needed. The blood pressure, respiration and pulse should also be monitered in cases of drug overdose. Other Sedating drugs should be withheld.
